Just dive in. Draw the first panel, draw the last, draw a couple in between. Rough sketches. Took me about ten minutes. Scanned it, posted it. A hit. Ta da, I was a Comic Artist.
Comic art is about life. You don’t have to be a comic to write a comic strip. Just pay extra attention to what’s going on in your day. Plenty of material there.
Use a square rather than a long rectangle. A square, two panels on top, two on the bottom. Versus a long rectangle of four panels in a row like a newspaper comic. The square work better for sharing images on line. You can see the whole square on Instagram, but not the rectangle.
One single square is best for the web. Attention is scarce on the web. I put my hand to web comics because I have learned that visuals work much better than text on the web. For the same reason, one square of content works better than four. Precious few will slow down enough to real four panels of story.
Keep your series short too. I intended to start a political comic with the subject changing day to day. Thing is, I started the day before the US election, figuring Hillary would win. The surprise outcome fueled a story 25 comics long. I have no doubt readers could not keep up with every post.
I prefer pencil colour over markers. Thin black ink is essential for contrast on the web. I tried colour markers and they come across more boldly, but I prefer the warmth and texture of pencil colour.
Mind your choice of paper for digital. 50 or 70 lb paper is nicer for hand drawing but shows yellower when you scan to digital. 100 lb “bristol” paper is hard and not so nice for drawing but scans clean white. Given my preference for pencil colour, I tradeoff at 70 lb.
Create a handwriting font of your own. Writing dialog or other text by hand is problematic. It is hard to space it right. Using a standard font loses character. A custom handwriting font is easy to build and keeps your charm. (Full disclosure. I still don’t have one that works just right. Soon.)
Use free digital tools. I draw by hand, then clean up and present using digital tools. I mix and remix the drawings, mostly using MS Paint. Paint does about 90% of what I need. More recently I have used the open source GIMP for complex layering.
Publish your comics on social media. I used a WordPress blog as my comic home, and distributed over Facebook, Twitter, Tumblr, Google+ and sometimes posted on Reddit. I built it. They came.